Thermoregulation in neonates with gastroschisis is important. Many factors cause loss of body heat and cause hypothermia in neonates with gastroschisis, including cold environments, differences in ratio between body surface area and body weight, low subcutaneous fat, low shivering ability to cold response and viscera organ exposed. Heat loss occurs through evaporation, convection, conduction, and radiation processes. Neonates with gastroschisis require urgent surgery to allow the exposed intestine to quickly close so that fluid loss and body heat from exposed viscera are resolved. Management of thermoregulation in neonate patients with gastroschisis begins preoperatively by preventing the loss of body heat from viscera organ exposed. It is important to avoid hypothermia by regulating the room temperature, using heating lights, blankets, heating mats, and using warm intravenous fluids. Hypothermia can lead to delayed recovery of anesthesia, coagulopathy, delayed wound healing which in turn increases the length of hospital care.